Healthcare cybersecurity must address requirements no other sector shares: medical device protection, EHR-aware threat detection, HIPAA-aligned audit trails, and continuity-of-care risk during incidents. The eight platforms below are the most commonly selected by hospital CISOs and integrated delivery networks following the 2024-2025 wave of healthcare ransomware incidents that elevated cybersecurity to a board-level concern.
Healthcare CISOs should weight selection on four dimensions: medical device and IoT security (which generic XDR rarely covers), EHR-aware detection that minimises clinical disruption, HIPAA and HITRUST attestation, and managed response that operates with awareness of clinical timing constraints.
Medical device security is the single largest gap in most health system cybersecurity programs. Connected devices number 10-15 per bed at large hospitals and rarely support endpoint agents. Specialist platforms — Medigate (now Claroty), Armis, Cynerio, and Asimily — discover, classify, and segment medical devices using passive network traffic analysis. EHR-aware detection minimises false positives that disrupt clinical workflow: Microsoft Defender for Healthcare and several EDR vendors now include Epic and Oracle Health behavioural baselines.
HIPAA and HITRUST attestation is table stakes for any platform in a HIPAA-covered environment; HITRUST CSF certification carries more weight than HIPAA attestation alone. Managed response with healthcare specialisation matters because contained playbooks must consider clinical impact: many MDR providers now operate dedicated healthcare practices. See our cybersecurity directory, best ERP for healthcare, and cybersecurity services.
| Product | Best for | Medical device | Rating | Starting price |
|---|---|---|---|---|
| Claroty xDome | Medical device security | Native | 4.5 | Per-device quote |
| Armis Centrix | Asset visibility + risk | Native | 4.4 | Per-device quote |
| CrowdStrike Falcon | EDR foundation | Via integrations | 4.6 | From $185/endpoint/yr |
| Defender for Healthcare | Microsoft-aligned IDNs | Via Defender for IoT | 4.3 | Bundled with E5 |
| Cynerio | IoMT-led security | Native | 4.4 | Per-device quote |
| Asimily | Mid-size hospitals | Native | 4.3 | Per-device quote |
| Cortex XDR Healthcare | Palo Alto-aligned systems | Via IoT Security | 4.4 | Custom quote |
| Forescout Medical | NAC + device segmentation | Native | 4.1 | Custom quote |